In the auditory system, function often directly follows form. Segregation of cell types in the organ of Corti and cochlear nucleus has revealed fundamental lessons about the biology of hearing. However, no such understanding exists at the level of the auditory cortex. By disambiguating the roles of distinct classes of projection neurons, our research program aims to understand the principles of cortical organization, and how such principles can give rise to complex behaviors.
Selected Recent Publications
M M. Asokan, R S. Williamson, K E. Hancock, D B. Polley (2017). Homeostatic normalization of sensory gain in auditory corticofugal feedback neurons following auditory deprivation. Nature Communications. 9(1), 2468
A F. Meyer, R S. Williamson, J F. Linden, M Sahani (2016). Models of neuronal stimulus-response functions: elaboration, estimation, and evaluation. Frontiers in Systems Neuroscience. 10(1): 109.
R S. Williamson, M B. Ahrens, J F. Linden, M Sahani (2016). Input-specific gain modulation by local sensory context shapes cortical and thalamic responses to complex sounds. Neuron. 91(2): 467-81.
R S. Williamson, K E. Hancock, B G. Shinn-Cunningham, D B. Polley (2015). Locomotion and task demands differentially modulate thalamic audiovisual processing during active search. Current Biology. 25, 1885-1891.
R S. Williamson, M. Sahani, J W. Pillow (2015). The equivalence of information-theoretic and likelihood-based methods for neural dimensionality reduction. PLoS Computational Biology. 11(4):e1004141
M. Sahani, R S. Williamson, M B. Ahrens, J F Linden (2013). Probabilistic methods for linear and multilinear models. In Handbook of Modern Techniques in Auditory Cortex, eds. D. Depirieux & M. Elhilali.